The Rise of Autism
Autism rates are rising, but is it an epidemic? Explore genetics, environment, diagnosis trends, and what autistic people truly want from research.
The early detection of folate receptor autoantibodies is necessary because it can lead to timely diagnosis and appropriate management of conditions associated with these autoantibodies. Folate receptor autoantibodies have been found in Cerebral Folate Deficiency Syndrome, Autism Spectrum Disorders, Schizophrenia, Depression and Neural Tube Defects, among other neurodevelopmental disorders.
FRAT® - developed in the lab of Dr. Edward Quadros at the State University of NY (SUNY Downstate) is the only assay available that can screen for BOTH blocking and binding folate receptor autoantibodies. FRAT®, as published in the New England Journal of Medicine, and used in numerous clinical trials, is the world’s leading diagnostic to detect these specific autoantibodies.
The timely initiation of appropriate treatment, such as alternate reduced folates and/or dietary adjustments, may lead to optimal outcomes and improved overall prognosis for the individual.
As with any medical test, the interpretation of the results and the subsequent treatment plan should be discussed with a qualified healthcare professional.
We continuously research the significance of folate receptor autoantibodies and their implications in various neurodevelopment and neuropsychiatric disorders.
Autism rates are rising, but is it an epidemic? Explore genetics, environment, diagnosis trends, and what autistic people truly want from research.
FDA approves leucovorin for cerebral folate deficiency linked to autism. Explore benefits, research, and why cautious optimism matters in autism treatment.
Learn how autism and OCD overlap, causing repetitive thoughts and actions, and how understanding “unstuck” helpers brings calm and safety to kids’ lives.
Cerebral Folate Deficiency (CFD) is a rare neurological disorder with low brain folate despite normal blood levels. Learn causes, symptoms & treatment.
Cow’s milk may trigger folate receptor autoantibodies, impairing folate transport to the brain and contributing to cerebral folate deficiency & ASD risk.
Learn how folic acid and folinic acid differ in metabolism, bioavailability, and their roles in health and medical treatments.
Explore autism and eating through Mia’s story. Learn how sensory needs, safe foods, and mealtime helpers support autistic children at the table.
Learn how folate receptor blocking and binding autoantibodies disrupt folate transport, cause cerebral folate deficiency, and affect neurodevelopment.
Explore how maternal metabolism adapts from pregnancy to lactation, fueling fetal growth and milk production for lifelong maternal and infant health.
Folate receptor autoantibodies, genetics & folate metabolism may raise birth defect risk. Learn how testing & tailored care can help prevent NTDs.
Discover how folate (vitamin B9) supports mitochondrial function, enhances ATP production, and protects against oxidative stress and chronic diseases.
Explore the metabolic shift at birth — from placental support to neonatal independence — and its impact on lifelong health and energy balance.
Discover how the FRAT® test detects folate receptor autoantibodies, aiding early diagnosis of autism, CFDS, and neuropsychiatric disorders for targeted treatment.
Understand the overlap between autism and dyslexia, how one can mask the other, and why a dual diagnosis is key for accurate support and intervention.
Learn about folate receptor autoantibodies (FRAAs), their role in subfertility, miscarriages, and potential treatments like folinic acid and methylfolate.
Explore how folate, B12, and mitochondrial metabolism shape autism’s biology—offering insights for diagnosis, treatment, and neurodevelopmental care.
Explore how folate impacts teenage depression, its symptoms, causes, and the role of folate receptor autoantibodies in mental health support.
Discover how folate impacts brain function, neurotransmitters, and inflammation—uncover its powerful role in preventing and managing depression.
Discover Mia’s story about autism and sleep. Learn why routines, sensory care, and calming support are key to helping autistic children rest well.